Writings

The Ageless Generation

How Advances in Biomedicine Will Transform the Global Economy

Seminal exploration of how biomedical advances in longevity will reshape healthcare, pensions, retirement, and the global economy. Written a decade before the longevity biotech boom.

Dating A.I.

A Guide to Falling in Love with Artificial Intelligence

Early exploration of human-AI relationships, written long before conversational AI entered the mainstream. Speculative and provocative in its predictions.

Artificial Intelligence for Healthy Longevity

Co-edited volume (Springer)

Co-edited multi-author reference establishing the canon for AI applications in aging research, drug discovery, and longevity biotechnology.

AI in Drug Discovery (chapter author)

Contributing author across multiple technical volumes

Chapters covering generative chemistry, deep learning for biology, GANs for de novo molecular design, and AI-enabled clinical trial prediction.

Majlis In The UAE: Peace, Tolerance, Diversity, Inclusion, And AI

Despite increasing conflicts in the Middle East, the UAE and Saudi Arabia remain at peace. Diversity, equity, tolerance and inclusion initiatives may be the reason.

Meta’s Release Of Llama 3 Changes Everything

Meta released its most capable open source LLM, Llama 3, which outperforms in most benchmarks. Here is what you need to know.

5 Tips To Enhance Your Research Paper’s Visibility And Altmetric Score

The Altmetric Attention Score measures the popularity of scientific articles. Here are 5 practical tips on how to boost your research paper’s visibility and score.

Can A Supplement Make Your Dog Live Longer?

New study by Animal Biosciences, a company co-founded by Harvard professor David Sinclair, suggests you may extend life and improve wellbeing of your furry companions.

“The Kardashian Of Longevity”: Is Bryan Johnson Good For The Nascent Longevity Biotechnology Industry?

Bryan Johnson is making headlines in tabloid and serious media around the world promoting his longevity regimen. What do serious scientists think about him?

Five AI-Powered Drug Discovery (AIDD) Industry Predictions For 2024

2024 will be a pivotal year for AI Drug Discovery (AIDD). Here are 5 Industry predictions from the industry insider perspective

Is There A Drug To Help You Lose Fat And Gain Muscle Without Exercise?

New weight loss drugs result in loss of muscle. Scientists at the University of Copenhagen showed that mice lacking TNIK gene stay lean & do not lose muscle when fed fat

Stanford Scientists Make A Breakthrough In Breast Cancer

One of the hottest cancer targets just got a boost in confidence. Stanford researchers published a PNAS paper on ENPP1 as an innate immune checkpoint in breast cancer

Merry AI Christmas: The Most Terrifying Thought Experiment In AI

Advances in AI and brain-computer interfaces may lead to the creation of AI that can read your mind. Will you fare well on AI Judgment Day?

Notes From ‘Davos In The Desert’: Threats And Hopes For The Global Economy

Insights from the meeting of the world's financial and industrial power brokers in Riyadh. Generative AI seems to the main hope for igniting global economic growth.

Can This Pharma CEO Change The Way Drugs Are Discovered, Developed, And Delivered With AI?

October 27, 2023 turned into Sanofi's "black Friday" as the company announced its intent to invest in internal R&D. The market did not get the message. Here is why.

Will There Be A Nobel Prize For AI?

While there is no Nobel Prize for AI, Jumper and Hassabis may be the frontrunners for a Nobel Prize in Chemistry for their discovery of AlphaFold

How Effective Is Big Pharma Internal R&D And How To Boost It?

The new blockbuster paper by the St Gallen consortium reveals the efficiency pharmaceutical R&D. The majority of the approved drugs were sourced externally.

What Is A Longevity Biotechnology Company?

There are many companies claiming to be in longevity biotechnology. But which ones qualify as longevity biotechnology companies?

You Are Likely To Live Longer Than You Think: Day Five Of The 10th ARDD Meeting Featuring Eli Lilly And Novo Nordisk

Like all things in life including life itself, the world's largest industry meeting in aging research came to a close. Here is a report on Day 5 of the meeting.

You Are Likely To Live Longer Than You Think: Day Four Of The 10th ARDD Meeting Featuring Minister Mette Kierkgaard

Day four out of five of the 10th ARDD was full of new revelations. For example we learned that that median lifespan of taurine-treated mice increased by 10 to 12%!

You Are Likely To Live Longer Than You Think: Day Three Of The 10th ARDD Meeting Featuring Dr. David Sinclair

David Sinclair and other top scientists presented their research at the 10th ARDD conference in Copenhagen

You Are Likely To Live Longer Than You Think

The report from the trenches of the second day of the 10th Aging Research for Drug Discovery, Copenhagen, August 29, 2023

Leaders In Longevity Medicine Convene In Copenhagen

Hundreds of aging research, drug discovery professionals, and clinicians convened in Copenhagen for the Longevity Medicine Day at the 10th ARDD.

OpenAI’s ChatGPT Crawler Bot Poses A Dilemma For Publishers And Newsmakers

Over time we saw the power shift from publishers and content creators to search engines. Will ChatGPT Bot trigger another redistribution of power and eat into publishers profits?

$6.16 Billion Per Drug Approval: Almost Half of Big Pharma Companies Hit Negative R&D Productivity

New study by the St Gallen consortium estimates the cost of one approved drug at $6.16 Billion. 7 of the top 16 pharma companies demonstrated negative R&D productivity.

AI Needs Its Own Day - But Should You Celebrate It On July 16th?

Artificial Intelligence needs its own day and there is substantial demand from the people willing to celebrate it. But should you celebrate it on July 16th?

New Breakthroughs In Cryopreservation Poised To Transform Organ Transplantation

In 2023, several breakthroughs have shaken the academic community. Freezing entire organs to sub-zero temperatures for future transplantation is now a reality.

Meet A VC On A Mission To Support Women In Longevity

The field of longevity biotechnology is rapidly evolving. Meet the venture capitalist dedicated to supporting and promoting female founders.

Sanofi Goes All-In On AI

Sanofi made a very important official announcement that went largely unnoticed by the media but has enormous implications for the company and pharmaceutical industry

Fostering International Collaboration In AI In Healthcare

Combining AI and robotics and healthcare with a mission to extend healthy human life. Meet Richard Yang, partner at Sinovation Ventures

US Updates National AI Strategy And Calls For Public Input

The White House released an update outlining the Biden-Harris administration's latest initiatives in formulating the national AI strategy, AI policies, and AI regulation.

Defying Danger and Aging: Sheba Longevity Medicine Center In Tel Aviv Launches Amidst Rocket Attacks

In May 2023, many longevity experts traveled to Israel despite the rocket attacks to open the world's first longevity medicine center at the Sheba Longevity Center

Aubrey De Grey Turns 60 - A 25-Year Journey In Biogerontology And The Longevity Escape Velocity Foundation

More than 25 years ago, Aubrey de Grey, a prominent but eccentric scientist embarked on a quest to fight aging. Today, he turned 60. He shared his thoughts on aging, longevity, an…

Women In Longevity And The Renaissance Of The SENS Research Foundation

In 2021, a scandal surrounding the SENS Foundation sent shockwaves through the longevity community. Now, with a restructured and female-led organization, the SENS Foundation perse…

Can We Enhance AI Safety By Teaching AI To Love Humans And Learning How To Love AI?

AI is getting increasingly better an many tasks and we are likely at the brink of another AI revolution. To make AI fundamentally safe and friendly, we need to become better as h…

From SEO To GEO: What GPT Marketers Need to Know

Generative AI is rapidly replacing and augmenting search. This transition will change the way search engine optimization (SOE) is done. Here is what you can do to prepare for the…

Inside The Largest Tech Event You Never Heard Of

A massive tech event attracting over 170 thousand people quietly transpired in Riyadh, Saudi Arabia. The country is making a giant leap from a theocracy to the vibrant technocracy…

Women In Longevity Making Longevity Accessible To All

The longevity biotechnology industry is attracting more funding and more people with new non-profits being formed to accelerate progress in the field. Meet Lisa Ireland, the pres…

Republican And Democratic Leaders Agree On This One Thing - Scientists Around The World Cheer!

There are many critical issues causing disagreement between the Republican and Democratic parties. These include the economy, foreign policy, gun control, abortion, immigration, c…

The Unexpected Winners Of The ChatGPT Generative AI Revolution

Generative AI is taking the world by the storm with billions invested in infrastructure, data, and people. The ability to generate human-level responses to complex queries is expe…

Meet The Muslim Female Physician Scientist Working To Extend The Health Span Of Emiratis

The MENA countries are joining the quest to extend healthy productive longevity. Meet Her Excellency Dr. Maryam Matar who is spearheading the healthy longevity initiatives in the…

Can Google Challenge OpenAI With Self-Attention Patents?

ChatGPT is taking the world by storm. At its core, it uses the self-attention methods pioneered and patented by Google. Will Google try to seek licensing fees or sue OpenAI in cou…

Will OpenAI End Google’s Search Monopoly?

Search is possibly one of the main technological advances of the Internet era that did not change much over the past 20 years. Now, we are in for another disruption. The real batt…

10 Reasons Why Collaboration With China Will Help Billions Of People Worldwide Live Longer And Healthier

It takes over a decade and over $2 Billion to discover and develop a new drug and the process fails over 90% of the time. Biotechnology is one of the areas where China and US must…

AI In Big Pharma: The First Antibody Designed Using AI In The Clinic

In recent years, a hand full of AI startup companies that managed to utilize AI/ML to discover novel targets and/or design therapeutics reached human clinical trials and received…

Can You Transplant A Brain Into A Young New Body? And Would You?

Imagine that you can grow a clone with the level of intelligence below the level of a turkey or a chicken with the perfectly-exercised body. Would you consider swapping your brain…

This Female AI Scientist Quietly Built A Profitable Longevity Startup In Estonia That Is Dominating The Global Skincare AI Market

She wanted to go into longevity but also wanted to enable the entire skincare industry. Artificial Intelligence turned out to be the optimal tool. Now she works with almost every…

This Harvard Female Scientist Wants To Use Genetics To Reverse The Age Of Your Skin

She worked in top labs at Stanford and Harvard. Now she wants to disrupt a 100-Billion-Dollar market by rejuvenating your skin using genetic engineering.

Think Outside The (Titanium) Box: Isochoric Cryopreservation Could Save Lives

While the recent advances in rapid reheating, novel antifreeze agents, are bringing humanity's dream for plug-and-play organs closer to reality. Here is another technology worthy…

Can We Reverse Our Psychological Age And Get Happier At The Same Time Using Artificial Intelligence?

As the body grows old, our minds are often instigated by mental decline and progressive, natural psychological aging. However, while there are very little we can do about biologic…

Inside Saudi Arabia’s $20 Billion Bet On Longevity Biotechnology

National investments in longevity biotechnology may result in new drugs that will help everyone on the planet live longer and provide new platforms for drug discovery. Surprisingl…

The Spring Of Cryobiology: One Enabling Technology That Will Help Build The New Industry Of The Future

For decades the field of cryobiology was largely ignored and underfunded. However, in recent years, several advances were made and will enable the creation of massively transforma…

Celebrity Strategy Consultant Predicts What Will Be The Most Impactful Area In The Pharmaceutical Industry

Aging is one single determinant of most diseases. In recent years, the biotechnology industry started using aging biology as a platform for drug discovery to discover and develop…

Going Beyond Target Or Mechanism Of Disease: Disruptive Innovation In Drug Delivery Systems

Identifying novel targets and designing novel molecules is not the only way to innovate in the biopharmaceutical industry. Sometimes, innovation in delivery systems for well-know…

When Will AI Beat The Eroom’s Law In The Pharmaceutical Industry?

The term Eroom’s law in pharma was coined by Dr. Jack Scannell and colleagues in 2012 in Nature Reviews Drug Discovery. It is the opposite of Moore's law in semiconductors and sta…

The 9th ARDD: Longevity Biotechnology Is Gaining Prominence And Credibility In The Pharmaceutical Industry

Aging research is rapidly gaining popularity in the pharmaceutical industry. Many pharmaceutical companies are working on dual-purpose programs targeting aging and disease. At the…

Elon Musk’s Babies Were Conceived Via IVF And Surrogacy - Is It The Future Of Reproduction?

The global population is aging and developed countries are experiencing population decline. At the same time, startups working on reproductive longevity, IVF and artificial uterus…

The New Saudi Arabia - Vision 2030 and AI

While the media focuses on the negative news to grab your attention, the world is rapidly improving. One of the pockets of this positive change is Saudi Arabia which recently comm…

A Week At The Most Secretive Conference On Aging

One of the most prestigious scientific conference series is the Gordon Research Conference (GRC). This is where prominent academics come to share their research openly but it is n…

The Advent Of Longevity Technology - From A Movement Into An Industry

Longevity biotechnology it is clearly one of the main industries of the future with thousands of new scientists and industry professionals entering the field every year. Here is a…

Can Viagra Extend Your Life?

Did you know that Viagra was originally developed as a cardiovascular drug and was implicated in ED by accident? Did you know that other pharma companies missed out on ED as they…

A Weekend By Foresight Institute - A Community For Future Technologies

There are many technologies that are rapidly advancing and converging. Longevity biotechnology is not standing still. Here are the highlights from a recent Foresight Institute mee…

Can We Fix Ovarian Aging? Here Is One Startup Up For The Task!

The field of female reproductive longevity and inequality is getting hot. The top venture capital firms are investing in this area. Oviva Therapeutics incubated by Cambrian Biosci…

What Are The Most Productive Pharmaceutical Companies?Pharmaceutical R&D Efficiency Review 1999-2018

The biopharmaceutical industry spends roughly $100 Billion annually on R&D. With over $2.6 Billion per drug approval it is among the most inefficient industries on the planet. But…

BioBAY Suzhou - China’s Biotechnology Megahub

One of the centers that impressed me the most in recent years was BioBay in Suzhou. It is the home to the many biotechnology and technology companies some of which reached a unico…

Over 10,000 Diseases And Only 50 Drugs Approved In 2021. To Improve Pharma R&D Efficiency We Need To Understand It.

Measuring the efficiency of research and development (R&D) in the pharmaceutical industry has long been a difficult task. It is even more complex now as many new technologies beco…

Measuring Attention In Science And Technology

Most people pay attention to the Kardashians, Trump, videos of cute kittens and ignore breakthroughs in science and technology even when it comes to human health. How do we make…

What Do ALS And War Have In Common?

Both war and ALS are terrible diseases that we need to learn to cure and prevent. Both require our immediate action. Some of the immediate treatments may be symptomatic making the…

Converging AI And Longevity Research: Cutting Edge Innovation In Insurtech At HITS

The convergence of artificial intelligence, aging research, distributed ledger technologies, new sensors, augmented and virtual reality is driving innovation in health and life in…

Forever In Love And In Love With Forever: Introducing The World’s First True Longevity Couple

Imagine working in the industry which aims to make life longer alongside the love of your life. The longevity biotechnology industry is growing rapidly and there are many scientis…

How AI And Aging Research Can Help Life Insurance Companies?

Imagine a world, where the average life expectancy exceeds 100 years. Thanks to investments and research in longevity biotechnology made in the last few years, coupled with more i…

Don’t Let The Old Man In: How To Develop A Longevity Mindset And Fight Psychological Aging?

We often look at our parents and grandparents to predict how long we are going to live and how fast we are going to age. But technology is not standing still and you may benefit f…

Nature Is Sexist. Can Advances In Longevity Biotechnology Help Restore Reproductive Equality?

There is a new season of women bound together by life experiences and by the realized necessity of optionality. The option of having a successful career without foregoing having…

Can The Pharmaceutical Companies Use Basic Aging Biology To Develop Drugs For Age-Related Diseases?

Aging research, drug discovery and development, and artificial intelligence are rapidly converging and resulting in new diagnostics and therapeutics. The conference covering these…

The Original Inventor Of “Metaverse” On Technology, Life, And Books: Interview With Neal Stephenson

Few people know that the concept of the "Metaverse" and virtual real estate was first proposed and described 30 years ago by Neal Stephenson in "Snow Crash". Here is an interview…

Billionaires Secretly Terraforming Earth And Other Reasons To Read “Termination Shock”

Climate change is real – both human-induced, human-accelerated, and natural. Its effects are already devastating and many entrepreneurs have stepped up to the challenge. But is i…

5 Ways To Stay Younger And More Creative As You Get Older

More than ever, we are seeing other examples of seniors in their eighties and beyond continuing to enrich the world with their achievements instead of settling into the decrepit o…

Spend Time To Make Time: Should Video Game Developers Get Into Healthcare?

Video game developers are producing more and more highly-addictive content that carries little educational value. Recent advances in longevity biotechnology may help gamers regain…

Can Advances In Aging Research Help You Overcome The Mid-Life Crisis?

In 1957, Canadian psychoanalysis Elliot Jacques first presented a paper to the British Psychoanalytical Society describing his case for a “midlife crisis” (though he never claimed…

Aging Brings Us Closer To Death. Why Do We Get Happier As We Age?

People who experience joyful events such as getting married or the birth of a first child find that joy fading as they adjust to how their lives have changed.

10 Tips For Reversing Your Psychological Age

While we’re still unable to take complete control of the physiological processes underlying aging, medical researchers have made some exciting breakthrough which may bring us even…

The Science And Technology Of Growing Young

The field of longevity biotechnology is rapidly evolving and new advances are being published every day. The new book by the venture capitalist and longevity enthusiast, Sergey Yo…

No Shame In Wanting To Look Younger - It Is Natural And You Might As Well Live Longer

Many people that have very harmful habits like smoking but still diet and exercise to look younger. It is a natural desire which evolved out of our need to stay attractive and re…

Wu Dao 2.0 - Bigger, Stronger, Faster AI From China

In many areas of artificial intelligence China has caught up or surpassed the other countries. And the Wu Dao 2.0 system presented at the annual BAAI conference is a testament to…

Mind Over Body: Can We Control Psychological Aging?

Aging is the universal equalizer. After we reach our peak age of around 25-35 we start losing physical performance. But we also age on the psychological level. And this is one are…

How To Stay Famous After You Die. AI Scientists Have An Answer

Do you know what will happen to your name after you die? A group of AI scientists analyzed mentions of a massive number of public figures in news and social media one year before…

Elon Musk’s Big Neuralink Paper: Should We Prepare For The Digital Afterlife?

One of the companies working to develop a deeper connection between the human brain and computers is a startup called Neuralink. Let's look at their peer-reviewed paper with Elon…

Preparing For The Coming Currency Collapse - What If You Could Incorporate Yourself?

Imagine a world where instead of investing in companies you could invest in people. As blockchain technology advances and we are getting closer to the economic collapse driven by…

Women In Longevity – Dr. Joan Mannick On Clinical Development For Aging

In 2014 ResTORbio spun off out of Novartis and went public to try a longevity drug as a vaccine-potentiating agent in the elderly. The company was led by Dr. Joan Mannick, a physi…

How Two Undergraduate Scientists Uncovered One of the Pharmaceutical Industries Biggest Secrets

A team of undergraduates lead by a professor at Cold Spring Harbor demonstrated that many targeted drugs do not work as expected. Target discovery is the pharmaceutical industry's…

Women In Longevity - Dr. Christine Huang Yuan

In 2020 Forbes China published its China 30 under 30 list of the most successful entrepreneurs. One of these executives on the list representing the healthcare & science sector wa…

High School Students Preparing To Join The Fight Against Aging

Longevity biotechnology is the in industry of the future and just like in physics or math, some students are planning a career in aging research from a very early age. Learn from…

Women In Longevity – Bringing Science Of Aging To Aesthetic Medicine Dr. Stephanie Manson Brown

Dr. Manson Brown is the head of clinical development and vice president of R&D at Allergan Aesthetics at Abbvie and is one of the few longevity physicians who wears several hats a…

Capturing Biases In the Age Of AI - The Interview With The Founder Of Wikipedia Founder Jimmy Wales

Since its birth in 2001 Wikipedia became an integral part of peoples’ lives with pretty much every Google query drawing from this massive volunteer-built and run online encycloped…

Women In Longevity Medicine: Dr. Dina Radenkovic

The longevity medicine industry is rapidly evolving and we are witnessing the advent of a new profession - longevity physician. Incorporating deep aging clocks in her diagnostic a…

Women In Longevity Medicine And The Rise Of The Longevity Physician

Over the past decade, we witnessed massive convergence of biotechnology and information technology. And now we are witnessing the birth of a new field of longevity medicine, which…

Why Do We Do What We Do? Manipulating Yourself To Better Manipulate Others

Have you ever wondered what are the hidden motives behind your actions? Why do we convince ourselves to believe something that is simply not true? Why do we ignore aging and immin…

Conquering Metabesity: What Does The Government Do For The Longevity Of Their Citizens?

Accelerating progress in longevity biotechnology driven by new technologies like AI-powered aging clocks is slowly propagating into the clinical practice and consumer business. It…

Deep Dive Into Big Pharma AI Productivity: One Study Shaking The Pharmaceutical Industry

The pharmaceutical business is perhaps the only industry on the planet, where to get the product from idea to market the company needs to spend about a decade, several billion dol…

This Stanford Scientist Can Make You Feel And Think Younger: Interview With Dr. Laura Carstensen

Aging is a multifactorial process affecting every aspect of our lives. As we age our psychology and behavior changes. In this article, I interviewed the world's most influential e…

Biotechnology In the Time of COVID-19: Past, Present, and Future

Despite popular belief, the biotechnology and biopharmaceutical industry suffered immense losses as a result of the COVID-19 pandemic. As many hospitals have surpassed maximum cap…

Breaking Through The Glass Ceiling - A Spring For Women In Artificial Intelligence

Many women have historically seen both AI and drug discovery as predominantly male professions.

AI Hype Or AI Hope: When Will AI Disrupt The Pharmaceutical Industry?

Since 2014 deep learning systems started outperforming humans in many tasks. But when it comes to drug discovery the rate of progress is seemingly slow.

The Future Is Faster Than You Think Book Review: How To Learn About Exponential Technologies And Develop A Positive Mindset

When it comes to exponential technologies there are few people in the world more informed than Dr. Peter H. Diamandis, MIT- and Harvard-trained medical doctor who co-founded Singu…

The Rise of the Deep: Eric Topol's Deep Medicine To Stand The Test Of Time

Deep Medicine not only provides a helicopter view of AI for drug discovery and development but goes further into the limitations, regulatory and ethical considerations.

How To Live This Life Better: Effective Altruism In The Context Of Longevity

A quantified approach to altruism in the form of counting the quality-adjusted life years (QALY) generated globally may help humans and AI make better life decisions.

Longevity Vision Fund: Fueling The Longevity Biotechnology Boom We've Been Waiting For

The longevity industry gets a boost with the launch of a $100 million venture fund, Longevity Vision Fund, focused on longevity biotechnology and artificial intelligence.

If This Life Is A Video Game, What Are The Winning Rules?

If life is a video game, what are the winning rules? While there are many scoring mechanisms including money, reputation, kids, physical performance and others—one least-known and…

Is Life A Recursive Video Game?

The idea that we humans are living inside a simulation is not new. Many religions propose the existence of a creator—an omnipotent deity who formed the world and set its rules in…