Likes & Dislikes

A distilled view of Alex's preferences — drawn from the Longevity Pledge, Forbes essays, Forever.ai posts, and public interviews.

👍 Likes

👎 Dislikes

Vague anti-aging claims without data

'Longevity supplements' with no RCTs, no clocks, no mechanism of action.

Drug discovery without computation

Brute-force screening campaigns in 2026 — the world has moved on.

Short-termism in biotech investing

Aging and fibrosis don't fit a 12-month IRR — but the market will exist.

AI hype without peer-reviewed results

A demo is not a drug. Patents are not clinical evidence. Publish.

Siloed data

Proprietary datasets locked away from federated learning slow the whole field.

Regulatory paralysis on aging as an indication

Aging is not a disease bucket at FDA — this blocks the biggest prize in medicine.

Over-reliance on a single target or mechanism

Single-target bets lose; platforms win. That's why we build platforms.

Fear-of-missing-out on foundation models

Big generic LLMs ≠ domain-specific generative chemistry. Physics-aware matters.

Travel downtime

That's why it's Wi-Fi, papers, and keynote drafting at 30,000 feet.

'First mover' claims without Phase II data

Many claim first-in-class AI drugs. Very few have in-human efficacy.